АЦЕТА
Т (УК
С
УСНАЯ К.)
ИЗОБУТИРАТПРОПИОНАТ
БУТИРА
Т (МА
С
ЛЯНАЯ К.)
2-МЕТИЛБУТИРАТВАЛЕРА
Т (В
АЛЕРИАНОВ
АЯ К.)
ИЗОГЕКСАНОАТ
ГЕКСАНОА
Т (КА
ПРОНОВ
АЯ К.)
АКРИЛАТ
МЕТАКРИЛАТКРОТОНАТ
ТИГЛАТ
2,3-ДИДЕГИДРО-
ВАЛЕРАТ
2,3-ДИДЕГИДРО-
ИЗОГЕКСАНОАТ
2,3-ДИДЕГИДРО-
ГЕКСАНОАТ
3-ГИДРОКСИГЕКСАНОАТ
3-ГИДРОКСИ-
ИЗОГЕКСАНОАТ
3-ГИДРОКСИВАЛЕРАТ
2-МЕТИЛ-3-ГИДР-
ОКСИБУТИРАТ
3-ГИДРОКСИБУТИРАТ
2-МЕТИЛ-3-ГИДРОКСИ-
ПРОПИОНАТ
3-ГИДРОКСИ-
ПРОПИОНАТ
МАЛОНИЛ-
ПОЛУАЛЬДЕГИД
МЕТИЛМАЛОНИЛ-
ПОЛУАЛЬДЕГИД
АЦЕТОАЦЕТАТ
2-МЕТИЛ-
АЦЕТОАЦЕТАТ
3-ОКСОВАЛЕРАТ
3-ОКСОИЗОГЕКСАНОАТ
3-ОКСОГЕКСАНОАТ
АДИПАТ
ЭТИЛМАЛОНАТ
СУКЦИНАТ
(ЯНТАРНАЯ К.)
МЕТИЛМАЛОНАТ
МАЛОНАТ
ОКСАЛАТ
(ЩАВЕЛЕВ
АЯ К.)
ФУМАРА
Т (т)
МАЛЕА
Т (ц)
?
?
3-ОКСОАДИПАТ
ОКСАЛОАЦЕТАТ
МАЛА
Т (ЯБЛОЧНАЯ К.)
Рис.1. Периодические после
довате
льности реакций ме
табо
лизма линейных и ра
зветв
ленных жирных кисл
от
. Красными
жирными стре
лк
ами обо
зна
чены реакции, участвующие в цикле лимонной кисл
о
ты (см. рис. 7). Черными жирными
стре
лк
ами обо
зна
чены реакции, участвующие в биосинт
ез
е изопреноидов и г
омоиз
опреноидов (см. рис. 4).
H
3
CCOOH/CoA
2.8.3.8/M
3.1.2.1/M6.2.1.1/M6.2.1.13/
H
3
C
2.8.3.1/
H
2
CCOOH/CoA
6.2.1.1/M6.2.1.17/M>
H
3
C
H
3
CCCOOH/CoA
H
H
3
C
H
2
C
2.8.3.1/
H
2
CCOOH/CoA
2.8.3.8/
6.2.1.2/M>
H
3
C
H
2
C
H
3
CCCOOH/CoA
H
H
3
C
(H
2
C)
2
2.8.3.8/
H
2
CCOOH/CoA
H
3
C
HCCH
3
H
2
C
2.8.3.8/
H
2
CCOOH/CoA
H
3
C
(H
2
C)
3
H
2
CCOOH/CoA
6.2.1.14/
(AcCoA)
(AcCoA)(AcCoA)(AcCoA)(AcCoA)(AcCoA)
(AcCoA)
(PrCoA)(PrCoA)
H
2
C
HCCOOH/CoA
6.2.1.1/M6.2.1.17/M
H
2
C
H
3
CCCOOH/CoA
H
3
C
HC
HCCOOH/CoA
6.2.1.2/M>
H
3
C
H
2
C
H
3
CCCOOH/CoA
H
3
C
H
2
C
HC
HCCOOH/CoA
H
3
C
HCCH
3
HC
HCCOOH/CoA
H
3
C
(H
2
C)
2
HC
HCCOOH/CoA
CO
2
CO
2
CO
2
H
3
C
HOCH
5.1.2.3R-SM
H
2
CCOOH/CoA
6.2.1.16/S6.2.1.2/M>
H
3
C
HOCH
H
3
CCCOOH/CoA
H
H
3
C
H
2
C
HOCH
H
2
CCOOH/CoA
H
3
C
HCCH
3
HOCH
H
2
CCOOH/CoA
H
3
C
(H
2
C)
2
HOCH
H
2
CCOOH/CoA
MMCoA
MMCoA
MCoAMCoAMCoAMCoAMCoAMCoAMCoA
H
3
C
2.8.3.5/M>
OC
3.1.2.11/M
H
2
CCOOH/CoA
6.2.1.16/M
H
3
C
OC
H
3
CCCOOH/CoA
H
H
3
C
H
2
C
OC
H
2
CCOOH/CoA
H
3
C
HCCH
3
OC
H
2
CCOOH/CoA
H
3
C
(H
2
C)
2
OC
H
2
CCOOH/CoA
CO
2
CO
2
CO
2
CO
2
CO
2
CO
2
CO
2
HOCH
2
3.1.2.4/M
H
2
CCOOH/CoA
HOCH
2
3.1.2.4/M
H
3
CCCOOH/CoA
H
HCO
H
2
CCOOH/CoA
2.8.3.5/M
HCO
H
3
CCCOOH/CoA
H
2.8.3.2/
HOOCCOOH/CoA
6.2.1.8/
H
2
CCOOH
COOH/CoA
2.8.3.3/2.8.3.5/M
H
3
C
5.1.99.1S-R
HCCOOH
COOH/CoA
3.1.2.17/M
H
2
CCOOH//Lip
H
2
CCOOH/CoA
6.2.1.4/M3.1.2.1/M2.8.3.2/
6.2.1.5/M3.1.2.3/M
2.8.3.5/M
H
3
C
H
2
C
HCCOOH
COOH/CoA
COOH
(H
2
C)
4
COOH/CoA
6.2.1.23/
AcAcCoA
HCCOOH
HOOCCH
5.2.1.1C-T
H
2
CCOOH/CoA
HOCCOOH
H
6.2.1.9/
H
2
CCOOH
OCCOOH
H
2
CCOOH
H
2
C
OC
2.8.3.6/
H
2
CCOOH/CoA
R-C
/4.2.1.17/S-TM
/4.2.1.55/RM
/4.2.1.58/RM>
/4.2.1.17/M
S-TR-C
/4.2.1.17/M
S-TR-C
1.1.1.30RM
/1.1.1.35/SM>
/1.1.1.36/R
/1.1.1.100/RM>
/1.1.1.157/S
1.1.1.30RM>
1.1.1.59
1.1.1.31
ЖИРНЫЕ КИС
ЛОТЫ
/1.3.99.3/M>
/1.3.1.8/M
/1.3.1.9/
/1.3.1.10/>
/1.3.99.2/M>
/1.3.1.8/M
/1.3.1.8/M
/1.3.99.12/M
/1.3.99.12/M
/1.3.1.8/M
(/[1;22]/)
/[1;22]/
/[1;22]/
(/2.3.1.16/M)
/2.3.1.38/M
/2.3.1.39/M
/2.3.1.41/M
(/2.3.1.16/M)
/[1;22]/
(/2.3.1.16/M)
(/2.3.1.16/M)
2.3.1.85
(/2.3.1.16/M)
2.3.1.111
(/2.3.1.9/M)
/2.3.1.38/M
/2.3.1.39/M
/2.3.1.41/M
1.2.1.18/*M
1.2.1.27/*M
/4.1.1.9/
/6.4.1.2/BSM
1.2.1.27/*M
/2.1.3.1/BSM
/4.1.1.41/BSM
/6.4.1.3/BSM
/6.4.1.3/BSM
R-C
/4.2.1.17/S-TM>
/4.2.1.59/R>
/1.1.1.178/SS
1.2.1.15
1.2.1.18/*M
1.2.1.27/*M
1.2.1.27/*M
/5.4.99.2/RM
[3]
1.3.5.1T
1.3.99.1TM
/[21]/
3.7.1.1
4.2.1.2
S-T
M
4.2.1.31R-C
4.2.1.34
S-T
1.1.1.37SM>
1.1.1.82S
1.1.3.3
S
1.1.99.7S
1.1.99.16S
<p>Sat Jul 24 05:14:30 EDT 2021</p>
<p>Sat Jul 24 05:14:44 EDT 2021</p>
<p>Sat Jul 24 05:14:53 EDT 2021</p>
<p>Sat Jul 24 05:15:02 EDT 2021</p>
<p>Sat Jul 24 05:15:10 EDT 2021</p>
<p>Sat Jul 24 05:15:20 EDT 2021</p>
<p>Sat Jul 24 05:15:29 EDT 2021</p>
<p>Sat Jul 24 05:15:43 EDT 2021</p>
<p>Sat Jul 24 05:16:04 EDT 2021</p>
<p>Sat Jul 24 05:16:16 EDT 2021</p>
<p>Sat Jul 24 05:16:26 EDT 2021</p>
<p>Sat Jul 24 05:16:36 EDT 2021</p>
<p>Sat Jul 24 05:16:54 EDT 2021</p>
<p>Sat Jul 24 05:17:03 EDT 2021</p>
<p>Sat Jul 24 05:17:12 EDT 2021</p>
<p>Sat Jul 24 05:17:22 EDT 2021</p>
<p>Sat Jul 24 05:17:31 EDT 2021</p>
<p>Sat Jul 24 05:17:46 EDT 2021</p>
<p>Sat Jul 24 05:19:05 EDT 2021</p>
<p>Sat Jul 24 05:19:13 EDT 2021</p>
<p>Sat Jul 24 05:19:25 EDT 2021</p>
<p>Sat Jul 24 05:19:36 EDT 2021</p>
<p>Sat Jul 24 05:19:45 EDT 2021</p>
<p>Sat Jul 24 05:19:55 EDT 2021</p>
<p>Sat Jul 24 05:20:08 EDT 2021</p>
<p>Sat Jul 24 05:20:19 EDT 2021</p>
<p>Sat Jul 24 05:20:29 EDT 2021</p>
<p>Sat Jul 24 05:20:39 EDT 2021</p>
<p>Sat Jul 24 05:20:48 EDT 2021</p>
<p>Sat Jul 24 05:20:56 EDT 2021</p>
<p>Sat Jul 24 05:21:11 EDT 2021</p>
<p>Sat Jul 24 05:21:20 EDT 2021</p>
<p>Sat Jul 24 05:21:35 EDT 2021</p>
<p>Sat Jul 24 05:21:43 EDT 2021</p>
<p>Sat Jul 24 05:21:57 EDT 2021</p>
<p>Sat Jul 24 05:22:05 EDT 2021</p>
<p>Sat Jul 24 05:22:13 EDT 2021</p>
<p>Sat Jul 24 05:22:27 EDT 2021</p>
<p>Sat Jul 24 05:22:39 EDT 2021</p>
<p>Sat Jul 24 05:22:52 EDT 2021</p>
<p>Sat Jul 24 05:23:00 EDT 2021</p>
<p>Sat Jul 24 05:23:39 EDT 2021</p>
<p>Sat Jul 24 05:24:08 EDT 2021</p>
<p>Sat Jul 24 05:24:16 EDT 2021</p>
<p>Sat Jul 24 05:24:24 EDT 2021</p>
<p>Sat Jul 24 05:24:35 EDT 2021</p>
<p>Sat Jul 24 05:24:45 EDT 2021</p>
<p>Sat Jul 24 05:24:54 EDT 2021</p>
<p>Sat Jul 24 05:25:01 EDT 2021</p>
<p>Sat Jul 24 05:25:08 EDT 2021</p>
<p>Sat Jul 24 05:25:16 EDT 2021</p>
<p>Sat Jul 24 05:25:27 EDT 2021</p>
<p>Sat Jul 24 05:25:37 EDT 2021</p>
<p>Sat Jul 24 05:25:47 EDT 2021</p>
<p>Sat Jul 24 05:25:55 EDT 2021</p>
<p>Sat Jul 24 05:26:02 EDT 2021</p>
<p>Sat Jul 24 05:26:09 EDT 2021</p>
<p>Sat Jul 24 05:26:19 EDT 2021</p>
<p>Sat Jul 24 05:26:27 EDT 2021</p>
<p>Sat Jul 24 05:26:39 EDT 2021</p>
<p>Sat Jul 24 05:26:48 EDT 2021</p>
<p>Sat Jul 24 05:26:57 EDT 2021</p>
<p>Sat Jul 24 05:27:05 EDT 2021</p>
<p>Sat Jul 24 05:27:16 EDT 2021</p>
<p>Sat Jul 24 05:27:24 EDT 2021</p>
<p>Sat Jul 24 05:27:33 EDT 2021</p>
<p>Sat Jul 24 05:27:42 EDT 2021</p>
<p>Sat Jul 24 05:27:52 EDT 2021</p>
<p>Sat Jul 24 05:28:01 EDT 2021</p>
<p>Sat Jul 24 05:28:09 EDT 2021</p>
<p>Sat Jul 24 05:28:17 EDT 2021</p>
<p>Sat Jul 24 05:28:25 EDT 2021</p>
<p>Sat Jul 24 05:28:36 EDT 2021</p>
<p>Sat Jul 24 05:28:49 EDT 2021</p>
<p>Sat Jul 24 05:28:59 EDT 2021</p>
<p>Sat Jul 24 05:29:10 EDT 2021</p>
<p>Sat Jul 24 05:29:36 EDT 2021</p>
<p>Sat Jul 24 05:29:55 EDT 2021</p>
<p>Sat Jul 24 05:36:24 EDT 2021</p>
<p>Sat Jul 24 05:36:37 EDT 2021</p>
<p>Sat Jul 24 05:36:47 EDT 2021</p>
<p>Sat Jul 24 05:37:04 EDT 2021</p>
<p>Sat Jul 24 05:37:20 EDT 2021</p>
<p>Sat Jul 24 05:40:58 EDT 2021</p>
<p>Sat Jul 24 05:41:11 EDT 2021</p>
<p>Sat Jul 24 05:41:22 EDT 2021</p>
<p>Sat Jul 24 05:41:33 EDT 2021</p>
<p>Sat Jul 24 05:41:52 EDT 2021</p>
<p>Sat Jul 24 05:42:04 EDT 2021</p>
<p>Sat Jul 24 05:42:22 EDT 2021</p>
<p>Sat Jul 24 05:42:44 EDT 2021</p>
<p>Sat Jul 24 05:42:57 EDT 2021</p>
<p>Sat Jul 24 05:43:05 EDT 2021</p>
<p>Sat Jul 24 05:43:24 EDT 2021</p>
<p>Sat Jul 24 05:43:59 EDT 2021</p>
<p>Sat Jul 24 05:44:07 EDT 2021</p>
<p>Sat Jul 24 05:44:16 EDT 2021</p>
<p>Sat Jul 24 05:44:24 EDT 2021</p>
<p>Sat Jul 24 05:45:24 EDT 2021</p>
<p>Sat Jul 24 05:45:37 EDT 2021</p>
<p>Sat Jul 24 05:45:56 EDT 2021</p>
<p>Sat Jul 24 06:00:43 EDT 2021</p>
<p>Sat Jul 24 06:01:55 EDT 2021</p>
<p>Sat Jul 24 06:02:01 EDT 2021</p>
<p>Sat Jul 24 06:15:13 EDT 2021</p>
<p>Sat Jul 24 06:15:28 EDT 2021</p>
<p>Sat Jul 24 06:15:45 EDT 2021</p>
<p>Sat Jul 24 06:16:16 EDT 2021</p>
<p>Sat Jul 24 06:16:32 EDT 2021</p>
<p>Sat Jul 24 06:23:12 EDT 2021</p>
<p>Sat Jul 24 06:23:34 EDT 2021</p>
<p>Sat Jul 24 06:23:53 EDT 2021</p>
<p>Sat Jul 24 06:24:15 EDT 2021</p>
<p>Sat Jul 24 06:24:33 EDT 2021</p>
<p>Sat Jul 24 06:24:46 EDT 2021</p>
<p>Sat Jul 24 06:25:02 EDT 2021</p>
<p>Sat Jul 24 06:25:24 EDT 2021</p>
<p>Sat Jul 24 06:25:41 EDT 2021</p>
<p>Sat Jul 24 06:26:01 EDT 2021</p>
<p>Sat Jul 24 06:26:23 EDT 2021</p>
<p>Sat Jul 24 06:27:20 EDT 2021</p>
<p>Sat Jul 24 06:27:51 EDT 2021</p>
<p>Sat Jul 24 06:28:22 EDT 2021</p>
<p>Sat Jul 24 06:28:55 EDT 2021</p>
<p>Sat Jul 24 06:29:00 EDT 2021</p>
<p>Sat Jul 24 06:30:14 EDT 2021</p>
<p>Sat Jul 24 06:30:22 EDT 2021</p>
<p>Sat Jul 24 06:30:49 EDT 2021</p>
<p>Sat Jul 24 06:31:20 EDT 2021</p>
<p>Sat Jul 24 06:31:41 EDT 2021</p>
<p>Sat Jul 24 06:32:06 EDT 2021</p>
<p>Sat Jul 24 06:32:45 EDT 2021</p>
<p>Sat Jul 24 06:33:07 EDT 2021</p>
<p>Sat Jul 24 06:33:26 EDT 2021</p>
<p>Sat Jul 24 06:33:32 EDT 2021</p>
<p>Sat Jul 24 06:33:43 EDT 2021</p>
<p>Sat Jul 24 06:39:55 EDT 2021</p>
<p>Sat Jul 24 06:41:03 EDT 2021</p>
<p>Sat Jul 24 06:41:25 EDT 2021</p>
<p>Sat Jul 24 06:41:49 EDT 2021</p>
<p>Sat Jul 24 06:42:33 EDT 2021</p>
<p>Sat Jul 24 06:42:44 EDT 2021</p>
<p>Sat Jul 24 06:42:58 EDT 2021</p>
<p>Sat Jul 24 06:43:17 EDT 2021</p>
<p>Sat Jul 24 06:43:31 EDT 2021</p>
<p>Sat Jul 24 06:47:51 EDT 2021</p>
<p>Sat Jul 24 06:47:56 EDT 2021</p>
<p>Sat Jul 24 06:49:27 EDT 2021</p>
<p>Sat Jul 24 06:49:33 EDT 2021</p>
<p>Sat Jul 24 06:49:42 EDT 2021</p>
<p>Sat Jul 24 06:49:48 EDT 2021</p>
<p>Sat Jul 24 06:50:05 EDT 2021</p>
<p>Sat Jul 24 06:50:11 EDT 2021</p>
<p>Sat Jul 24 06:50:18 EDT 2021</p>
<p>Sat Jul 24 06:50:30 EDT 2021</p>
<p>Sat Jul 24 06:50:42 EDT 2021</p>
<p>Sat Jul 24 06:50:52 EDT 2021</p>
<p>Sat Jul 24 06:51:07 EDT 2021</p>
<p>Sat Jul 24 06:51:15 EDT 2021</p>
<p>Sat Jul 24 06:51:27 EDT 2021</p>
<p>Sat Jul 24 06:55:14 EDT 2021</p>
<p>Sat Jul 24 06:55:40 EDT 2021</p>
<p>Sat Jul 24 06:55:45 EDT 2021</p>
<p>Sat Jul 24 06:56:06 EDT 2021</p>
<p>Sat Jul 24 06:56:29 EDT 2021</p>
<p>Sat Jul 24 06:56:45 EDT 2021</p>
<p>Sat Jul 24 06:57:03 EDT 2021</p>
<p>Sat Jul 24 07:01:02 EDT 2021</p>
<p>Sat Jul 24 07:01:34 EDT 2021</p>
<p>Sat Jul 24 07:01:49 EDT 2021</p>
<p>Sat Jul 24 07:04:06 EDT 2021</p>